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Pets Health

Best Cat Arthritis Pain Medications

Updated August 2023
Bottom line
Pros
Cons
Best of the Best
Onsior Tablets for Cats, 6-mg, 3 tablets
Onsior
Tablets for Cats, 6-mg, 3 tablets
Controls Inflammation

The ultimate solution for your poor kitty’s post spaying or neutering discomfort, Onsior works quickly to efficiently reduce swelling and soothe your cat after simple soft tissue surgeries.

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Check Price
Controls Inflammation
Bottom Line

The ultimate solution for your poor kitty’s post spaying or neutering discomfort, Onsior works quickly to efficiently reduce swelling and soothe your cat after simple soft tissue surgeries.

Pros

Controls postoperative pain and inflammation. Non-narcotic. Nonsteroidal. Effective at relieving pain. Fast-acting. Once-per-day pill.

Cons

This is an expensive trio of pain relief pills, but this medicine is only intended to be taken for up to 3 days in a row anyway.

Best Bang for the Buck
Dexamethasone (Generic) Tablets for Dogs & Cats
Dexamethasone
(Generic) Tablets for Dogs & Cats
Bargain Pick

Inexpensive and rapidly controls pain and swelling from inflammation for a wide range of ailments, Dexamethasone is a comprehensive prescription for treating a cat’s persistent pain or arthritis.

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Bargain Pick
Bottom Line

Inexpensive and rapidly controls pain and swelling from inflammation for a wide range of ailments, Dexamethasone is a comprehensive prescription for treating a cat’s persistent pain or arthritis.

Pros

Extremely affordable. Available in 2 dosage sizes, 0.5mg and 0.75mg. Reduces inflammation. Helps to treat autoimmune diseases, blood disorders, bronchitis, some spinal cord diseases, certain types of colitis, and other inflammation-related conditions.

Cons

Side effects may include changes in appetite, increased thirst and urination, drowsiness, hyperglycemia, and muscle loss over long periods of use.

Methocarbamol (Generic) Tablets for Dogs & Cats
Methocarbamol
(Generic) Tablets for Dogs & Cats
Treats Muscle Spasms

If your little buddy is suffering from acute muscle spasms and needs help with resting or physical therapy, Methocarbamol may be the prescription solution your cat needs to jumpstart the healing process.

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Treats Muscle Spasms
Bottom Line

If your little buddy is suffering from acute muscle spasms and needs help with resting or physical therapy, Methocarbamol may be the prescription solution your cat needs to jumpstart the healing process.

Pros

Affordable. Available in 2 strengths, 500mg and 750mg. Treats acute and painful musculoskeletal conditions and muscle spasms. Easy to hide in a cat’s food. Reduces muscle tremors. Relaxes muscles.

Cons

Although Methocarbamol is effective at reducing painful muscle spasms, the effects are not long-lasting.

Prednisolone (Generic) Oral Solution, 15 mg/5 mL, 16-oz
Prednisolone
(Generic) Oral Solution, 15 mg/5 mL, 16-oz
Quick-relieving

Despite its fruity flavor, Prednisolone’s liquid formula is a surefire way to rapidly treat a cat’s inflammation from arthritis, stomach problems, muscular pains, and a number of other uncomfortable feline issues.

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Check Price at Chewy.com
Quick-relieving
Bottom Line

Despite its fruity flavor, Prednisolone’s liquid formula is a surefire way to rapidly treat a cat’s inflammation from arthritis, stomach problems, muscular pains, and a number of other uncomfortable feline issues.

Pros

Convenient liquid medicine. Treats pain and inflammation from autoimmune diseases, allergies, arthritis, breathing problems, skin issues, and other inflammatory conditions. Fast-acting formula.

Cons

Some cats may not appreciate the cherry or raspberry flavored medicine. Flavors are shipped out at random.

Piroxicam (Generic) Capsules, 10-mg, 1 capsule
Piroxicam
(Generic) Capsules, 10-mg, 1 capsule
Helps Arthritis Pain

Specifically formulated for blocking ongoing arthritis pain and reducing inflammation at the source, we recommend asking your veterinarian if Piroxicam is right for your cat.

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Helps Arthritis Pain
Bottom Line

Specifically formulated for blocking ongoing arthritis pain and reducing inflammation at the source, we recommend asking your veterinarian if Piroxicam is right for your cat.

Pros

Made to relieve pain and inflammation stemming from arthritis. Effective at treating a fever. Non-steroidal. Anti-inflammatory. Moderate per-capsule price.

Cons

Unless your cat is a well-trained saint, you’ll have to hide these capsules in kitty’s food or treats.

Why trust BestReviews?
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We only make money if you purchase a product through our links, and all opinions about the products are our own. About BestReviews  
BestReviews spends thousands of hours researching, analyzing, and testing products to recommend the best picks for most consumers. We buy all products with our own funds, and we never accept free products from manufacturers.About BestReviews 
HOW WE TESTED

We recommend these products based on an intensive research process that's designed to cut through the noise and find the top products in this space. Guided by experts, we spend hours looking into the factors that matter, to bring you these selections.

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First Reviewed
November 09, 2021
30
Models
considered
14
Hours
researched
Category cover
Melinda Harris
Written by Melinda Harris

Updated August 2023

It doesn’t matter if your favorite cat in the whole world is dealing with acute arthritis, a recent surgery, or stubbornly lingering pain, because you’re going to do everything you can to make your kitty feel better. The good news is that your veterinarian is able to prescribe a wide range of pain and arthritis medicines that will rapidly dull your cat’s pain, reduce inflammation, and fight off other irritating symptoms. Although we highly suggest listening to the vet regarding your cat’s pain or arthritis medicine, there are a few options to inquire about, including its form, ease of feeding, dosage, potential side effects, and affordability.

Our Top Picks
Onsior
Best of the Best
Onsior
Tablets for Cats, 6-mg, 3 tablets
Bottom Line
The ultimate solution for your poor kitty’s post spaying or neutering discomfort, Onsior works quickly to efficiently reduce swelling and soothe your cat after simple soft tissue surgeries.
Shop Now
Dexamethasone
Best Bang for the Buck
Dexamethasone
(Generic) Tablets for Dogs & Cats
Bottom Line
Inexpensive and rapidly controls pain and swelling from inflammation for a wide range of ailments, Dexamethasone is a comprehensive prescription for treating a cat’s persistent pain or arthritis.
Shop Now
Methocarbamol
Top Pick
Methocarbamol
(Generic) Tablets for Dogs & Cats
Bottom Line
If your little buddy is suffering from acute muscle spasms and needs help with resting or physical therapy, Methocarbamol may be the prescription solution your cat needs to jumpstart the healing process.
Shop Now
Prednisolone
Top Pick
Prednisolone
(Generic) Oral Solution, 15 mg/5 mL, 16-oz
Bottom Line
Despite its fruity flavor, Prednisolone’s liquid formula is a surefire way to rapidly treat a cat’s inflammation from arthritis, stomach problems, muscular pains, and a number of other uncomfortable feline issues.
Shop Now
Piroxicam
Top Pick
Piroxicam
(Generic) Capsules, 10-mg, 1 capsule
Bottom Line
Specifically formulated for blocking ongoing arthritis pain and reducing inflammation at the source, we recommend asking your veterinarian if Piroxicam is right for your cat.
Shop Now
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